BDBM50407998 CHEMBL144567

SMILES: CN1CCc2cc3N(CCc3cc12)C(=O)Nc1cccnc1

InChI Key: InChIKey=MFDGTFLMDIUFFP-UHFFFAOYSA-N

Data: 1 KI  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50407998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50407998 (CHEMBL144567) Show SMILES CN1CCc2cc3N(CCc3cc12)C(=O)Nc1cccnc1 Show InChI InChI=1S/C17H18N4O/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14/h2-3,6,9-11H,4-5,7-8H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from rat 5-HT2C receptor expressed in HEK293				J Med Chem 39: 4966-77 (1997) Article DOI: 10.1021/jm960571v BindingDB Entry DOI: 10.7270/Q2S75HJF
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2b (5HT2A and 5HT2B) (RAT)	BDBM50407998 (CHEMBL144567) Show SMILES CN1CCc2cc3N(CCc3cc12)C(=O)Nc1cccnc1 Show InChI InChI=1S/C17H18N4O/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14/h2-3,6,9-11H,4-5,7-8H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 5-HT binding to 5-HT2B receptor of Rat stomach fundus				J Med Chem 39: 4966-77 (1997) Article DOI: 10.1021/jm960571v BindingDB Entry DOI: 10.7270/Q2S75HJF
					More data for this Ligand-Target Pair