BDBM50408209 CHEMBL4173813

SMILES: CSc1[nH]c2c(ccc(c2c(=O)c1C(C)=O)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=OTIHLLALIMMLKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase Subunit A (Staphylococcus aureus)	BDBM50408209 (CHEMBL4173813) Show SMILES CSc1[nH]c2c(ccc(c2c(=O)c1C(C)=O)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C14H9F6NO2S/c1-5(22)8-11(23)9-6(13(15,16)17)3-4-7(14(18,19)20)10(9)21-12(8)24-2/h3-4H,1-2H3,(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
Anhui Medical University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase subunit A supercoiling activity using relaxed pBR322 DNA as substrate after 60 mins by agarose gel ele...				Eur J Med Chem 154: 144-154 (2018) Article DOI: 10.1016/j.ejmech.2018.05.021 BindingDB Entry DOI: 10.7270/Q2833VMP
					More data for this Ligand-Target Pair