BDBM50408251 CHEMBL2115094

SMILES: C[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](COCc1ccccc1)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)C(N)=O

InChI Key: InChIKey=KXDGVOMWEJNZDH-ANFZIGRPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50408251 (CHEMBL2115094) Show SMILES C[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](COCc1ccccc1)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)OCc1ccccc1)C(N)=O Show InChI InChI=1S/C47H51N9O9/c1-29(42(48)58)52-43(59)39(21-33-23-50-37-15-9-8-14-36(33)37)54-46(62)41(27-64-25-31-10-4-2-5-11-31)55-44(60)38(20-30-16-18-35(57)19-17-30)53-45(61)40(22-34-24-49-28-51-34)56-47(63)65-26-32-12-6-3-7-13-32/h2-19,23-24,28-29,38-41,50,57H,20-22,25-27H2,1H3,(H2,48,58)(H,49,51)(H,52,59)(H,53,61)(H,54,62)(H,55,60)(H,56,63)/t29-,38-,39+,40+,41+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against rat brain farnesyltransferase				J Med Chem 40: 192-200 (1997) Article DOI: 10.1021/jm960602m BindingDB Entry DOI: 10.7270/Q2JW8FJ4
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