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BDBM50408402 CHEMBL355444

SMILES: COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C#N

InChI Key: InChIKey=BRPYNELBFAAPRA-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408402   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))		BDBM50408402
PNG
(CHEMBL355444)
Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C#N
Show InChI InChI=1S/C25H25BrN4O2/c1-32-24-20-8-4-3-7-19(20)22(26)16-21(24)25(31)28-10-11-29-12-14-30(15-13-29)23-9-5-2-6-18(23)17-27/h2-9,16H,10-15H2,1H3,(H,28,31)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 50.1n/an/an/an/an/an/an/an/a



University Centre for Pharmacy

Curated by ChEMBL


Assay Description
Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log Ki

J Med Chem 40: 833-40 (1997)


Article DOI: 10.1021/jm9605952
BindingDB Entry DOI: 10.7270/Q23J3F5T
More data for this
Ligand-Target Pair