Found 3 hits for monomerid = 50408702 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50408702
(CHEMBL21790)Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2noc(C)n2)cc1CCCN(C)C Show InChI InChI=1S/C29H32N4O3/c1-19-17-24(28-30-20(2)36-32-28)12-14-26(19)21-8-10-22(11-9-21)29(34)31-25-13-15-27(35-5)23(18-25)7-6-16-33(3)4/h8-15,17-18H,6-7,16H2,1-5H3,(H,31,34) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1B receptor |
J Med Chem 41: 1218-35 (1998)
Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50408702
(CHEMBL21790)Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2noc(C)n2)cc1CCCN(C)C Show InChI InChI=1S/C29H32N4O3/c1-19-17-24(28-30-20(2)36-32-28)12-14-26(19)21-8-10-22(11-9-21)29(34)31-25-13-15-27(35-5)23(18-25)7-6-16-33(3)4/h8-15,17-18H,6-7,16H2,1-5H3,(H,31,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 2A receptor |
J Med Chem 41: 1218-35 (1998)
Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50408702
(CHEMBL21790)Show SMILES COc1ccc(NC(=O)c2ccc(cc2)-c2ccc(cc2C)-c2noc(C)n2)cc1CCCN(C)C Show InChI InChI=1S/C29H32N4O3/c1-19-17-24(28-30-20(2)36-32-28)12-14-26(19)21-8-10-22(11-9-21)29(34)31-25-13-15-27(35-5)23(18-25)7-6-16-33(3)4/h8-15,17-18H,6-7,16H2,1-5H3,(H,31,34) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor |
J Med Chem 41: 1218-35 (1998)
Article DOI: 10.1021/jm970457s BindingDB Entry DOI: 10.7270/Q2XS5WMN |
More data for this Ligand-Target Pair | |