BDBM50408888 CHEMBL417227

SMILES: CCc1c(C)[nH]c(=O)c(NC(=O)CNC(=O)CN)c1Cc1cc(C)cc(C)c1

InChI Key: InChIKey=LARRWOATVSWJNV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50408888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50408888 (CHEMBL417227) Show SMILES CCc1c(C)[nH]c(=O)c(NC(=O)CNC(=O)CN)c1Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C21H28N4O3/c1-5-16-14(4)24-21(28)20(25-19(27)11-23-18(26)10-22)17(16)9-15-7-12(2)6-13(3)8-15/h6-8H,5,9-11,22H2,1-4H3,(H,23,26)(H,24,28)(H,25,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
UMR 176 CNRS/Institut Curie Curated by ChEMBL					Assay Description Effective concentration required to achieve 50% inhibition of HIV-1 LAI replication in human T4 lymphoblastoid CEM-SS cells.				J Med Chem 43: 1927-39 (2000) BindingDB Entry DOI: 10.7270/Q2WS8VFT
					More data for this Ligand-Target Pair