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SMILES: Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(=C3N)c3ccccc3)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O

InChI Key: InChIKey=RSHBNVGRZTYOSF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409569   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50409569
PNG
(CHEMBL338643)
Show SMILES Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C(=C3N)c3ccccc3)C2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O |c:21|
Show InChI InChI=1S/C31H49N3O8SSi2/c1-20-18-34(28(36)33(8)26(20)35)27-25(41-45(11,12)30(5,6)7)31(22(40-27)19-39-44(9,10)29(2,3)4)24(32)23(43(37,38)42-31)21-16-14-13-15-17-21/h13-18,22,25,27H,19,32H2,1-12H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 1.70E+3n/an/an/an/a



Instituto de Qu£mica M£dica (C.S.I.C.)

Curated by ChEMBL


Assay Description
Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.

J Med Chem 45: 3934-45 (2002)


BindingDB Entry DOI: 10.7270/Q2639QXQ
More data for this
Ligand-Target Pair