null

SMILES: CNC1=C(C)S(=O)(=O)OC11C(CO[Si](C)(C)C(C)(C)C)OC(C1O[Si](C)(C)C(C)(C)C)n1cc(C)c(=O)n(C)c1=O

InChI Key: InChIKey=AVSFAZHQPPPHIY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50409574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409574 (CHEMBL413115) Show SMILES CNC1=C(C)S(=O)(=O)OC11C(CO[Si](C)(C)C(C)(C)C)OC(C1O[Si](C)(C)C(C)(C)C)n1cc(C)c(=O)n(C)c1=O |c:2| Show InChI InChI=1S/C27H49N3O8SSi2/c1-17-15-30(24(32)29(10)22(17)31)23-21(37-41(13,14)26(6,7)8)27(20(28-9)18(2)39(33,34)38-27)19(36-23)16-35-40(11,12)25(3,4)5/h15,19,21,23,28H,16H2,1-14H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in MT-4 cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50409574 (CHEMBL413115) Show SMILES CNC1=C(C)S(=O)(=O)OC11C(CO[Si](C)(C)C(C)(C)C)OC(C1O[Si](C)(C)C(C)(C)C)n1cc(C)c(=O)n(C)c1=O |c:2| Show InChI InChI=1S/C27H49N3O8SSi2/c1-17-15-30(24(32)29(10)22(17)31)23-21(37-41(13,14)26(6,7)8)27(20(28-9)18(2)39(33,34)38-27)19(36-23)16-35-40(11,12)25(3,4)5/h15,19,21,23,28H,16H2,1-14H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (C.S.I.C.) Curated by ChEMBL					Assay Description Effective concentration required to inhibit HIV-1 induced cytopathicity in CEM cell culture by 50%.				J Med Chem 45: 3934-45 (2002) BindingDB Entry DOI: 10.7270/Q2639QXQ
					More data for this Ligand-Target Pair