BDBM50409822 CHEMBL2111608

SMILES: O=C1Cc2ccccc2N1C1CCN(C[C@@H]2CC3CCC2C3)CC1

InChI Key: InChIKey=LJPUZFQIXKYVEE-HTWSVDAQSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50409822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50409822 (CHEMBL2111608) Show SMILES O=C1Cc2ccccc2N1C1CCN(C[C@@H]2CC3CCC2C3)CC1 |r,THB:14:15:21:19.18| Show InChI InChI=1S/C21H28N2O/c24-21-13-17-3-1-2-4-20(17)23(21)19-7-9-22(10-8-19)14-18-12-15-5-6-16(18)11-15/h1-4,15-16,18-19H,5-14H2/t15?,16?,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Nociceptin receptor on CHO cell membranes by [3H]N/OFQ displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50409822 (CHEMBL2111608) Show SMILES O=C1Cc2ccccc2N1C1CCN(C[C@@H]2CC3CCC2C3)CC1 |r,THB:14:15:21:19.18| Show InChI InChI=1S/C21H28N2O/c24-21-13-17-3-1-2-4-20(17)23(21)19-7-9-22(10-8-19)14-18-12-15-5-6-16(18)11-15/h1-4,15-16,18-19H,5-14H2/t15?,16?,18-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Opioid receptor mu 1 on CHO cell membranes was determined by [3H]DAMGO displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50409822 (CHEMBL2111608) Show SMILES O=C1Cc2ccccc2N1C1CCN(C[C@@H]2CC3CCC2C3)CC1 |r,THB:14:15:21:19.18| Show InChI InChI=1S/C21H28N2O/c24-21-13-17-3-1-2-4-20(17)23(21)19-7-9-22(10-8-19)14-18-12-15-5-6-16(18)11-15/h1-4,15-16,18-19H,5-14H2/t15?,16?,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	318	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human Opioid receptor kappa 1 on CHO cell membranes by [3H]U-69593 displacement.				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50409822 (CHEMBL2111608) Show SMILES O=C1Cc2ccccc2N1C1CCN(C[C@@H]2CC3CCC2C3)CC1 |r,THB:14:15:21:19.18| Show InChI InChI=1S/C21H28N2O/c24-21-13-17-3-1-2-4-20(17)23(21)19-7-9-22(10-8-19)14-18-12-15-5-6-16(18)11-15/h1-4,15-16,18-19H,5-14H2/t15?,16?,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Binding affinity against human opioid receptor delta 1 transfected on CHO cells was determined using [3H]Cl-DPDPE				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50409822 (CHEMBL2111608) Show SMILES O=C1Cc2ccccc2N1C1CCN(C[C@@H]2CC3CCC2C3)CC1 |r,THB:14:15:21:19.18| Show InChI InChI=1S/C21H28N2O/c24-21-13-17-3-1-2-4-20(17)23(21)19-7-9-22(10-8-19)14-18-12-15-5-6-16(18)11-15/h1-4,15-16,18-19H,5-14H2/t15?,16?,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
SRI International Curated by ChEMBL					Assay Description Concentration required for stimulation of [35S]-GTP-gammaS, binding to human Nociceptin receptor in cell membranes				J Med Chem 47: 2973-6 (2004) Article DOI: 10.1021/jm034249d BindingDB Entry DOI: 10.7270/Q2KW5FHV
					More data for this Ligand-Target Pair