BDBM50409965 CHEMBL373188
SMILES: CC(=O)NCCCCCc1csc(Cc2ccc(cc2)S(=O)(=O)Nc2ccc(CCNC[C@H](O)c3ccccc3)cc2)n1
InChI Key: InChIKey=VQOAYUJCYISDCB-YTTGMZPUSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-3 adrenergic receptor (Homo sapiens (Human)) | BDBM50409965 (CHEMBL373188) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
S.G.S.I.T.S. Curated by ChEMBL | Assay Description Effective concentration to stimulate cAMP production in chinese hamster ovary cells expressing cloned human beta-3-adrenergic receptor | Bioorg Med Chem Lett 15: 3167-73 (2005) Article DOI: 10.1016/j.bmcl.2005.03.119 BindingDB Entry DOI: 10.7270/Q26111JS | |||||||||||
More data for this Ligand-Target Pair |