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BDBM50409981 CHEMBL371247

SMILES: O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(CCc3nc(Cc4ccc5ccccc5c4)cs3)cc2)cc1)c1ccccc1

InChI Key: InChIKey=JJGWWEDESAXGQO-QNGWXLTQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409981   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50409981
PNG
(CHEMBL371247)
Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(CCc3nc(Cc4ccc5ccccc5c4)cs3)cc2)cc1)c1ccccc1
Show InChI InChI=1S/C38H37N3O3S2/c42-37(32-7-2-1-3-8-32)26-39-23-22-29-11-17-34(18-12-29)41-46(43,44)36-19-13-28(14-20-36)15-21-38-40-35(27-45-38)25-30-10-16-31-6-4-5-9-33(31)24-30/h1-14,16-20,24,27,37,39,41-42H,15,21-23,25-26H2/t37-/m0/s1
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Similars
Article
PubMed
n/an/an/an/a 12n/an/an/an/a



S.G.S.I.T.S.

Curated by ChEMBL


Assay Description
Effective concentration to stimulate cAMP production in chinese hamster ovary cells expressing cloned human beta-3-adrenergic receptor

Bioorg Med Chem Lett 15: 3167-73 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.119
BindingDB Entry DOI: 10.7270/Q26111JS
More data for this
Ligand-Target Pair