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BDBM50409982 CHEMBL371220

SMILES: O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cc3nc(cs3)-c3cnc4ccccc4c3)cc2)cc1)c1ccccc1

InChI Key: InChIKey=WOMSAMQUKONRNK-UMSFTDKQSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409982   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-3 adrenergic receptor


(Homo sapiens (Human))		BDBM50409982
PNG
(CHEMBL371220)
Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(Cc3nc(cs3)-c3cnc4ccccc4c3)cc2)cc1)c1ccccc1
Show InChI InChI=1S/C35H32N4O3S2/c40-34(27-6-2-1-3-7-27)23-36-19-18-25-10-14-30(15-11-25)39-44(41,42)31-16-12-26(13-17-31)20-35-38-33(24-43-35)29-21-28-8-4-5-9-32(28)37-22-29/h1-17,21-22,24,34,36,39-40H,18-20,23H2/t34-/m0/s1
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Similars
Article
PubMed
n/an/an/an/a 7.30n/an/an/an/a



S.G.S.I.T.S.

Curated by ChEMBL


Assay Description
Effective concentration to stimulate cAMP production in chinese hamster ovary cells expressing cloned human beta-3-adrenergic receptor

Bioorg Med Chem Lett 15: 3167-73 (2005)


Article DOI: 10.1016/j.bmcl.2005.03.119
BindingDB Entry DOI: 10.7270/Q26111JS
More data for this
Ligand-Target Pair