BDBM50409993 CHEMBL362576

SMILES: COc1ccc(cc1OC)-c1cn(C)nc1-c1cc(Cl)c(O)cc1O

InChI Key: InChIKey=LYRUENRNVMISHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50409993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent molecular chaperone HSP82 (Saccharomyces cerevisiae)	BDBM50409993 (CHEMBL362576) Show SMILES COc1ccc(cc1OC)-c1cn(C)nc1-c1cc(Cl)c(O)cc1O Show InChI InChI=1S/C18H17ClN2O4/c1-21-9-12(10-4-5-16(24-2)17(6-10)25-3)18(20-21)11-7-13(19)15(23)8-14(11)22/h4-9,22-23H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of yeast Hsp90 ATPase activity				Bioorg Med Chem Lett 15: 3338-43 (2005) Article DOI: 10.1016/j.bmcl.2005.05.046 BindingDB Entry DOI: 10.7270/Q22808T2
					More data for this Ligand-Target Pair