BDBM50410001 CHEMBL368233

SMILES: O=C(Nc1cccc(c1)-c1ccnc2c(cnn12)C(=O)c1cccs1)C1CC1

InChI Key: InChIKey=BVGGOIHWEOZOKN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50410001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK-interacting protein 1 (Homo sapiens (Human))	BDBM50410001 (CHEMBL368233) Show SMILES O=C(Nc1cccc(c1)-c1ccnc2c(cnn12)C(=O)c1cccs1)C1CC1 Show InChI InChI=1S/C21H16N4O2S/c26-19(18-5-2-10-28-18)16-12-23-25-17(8-9-22-20(16)25)14-3-1-4-15(11-14)24-21(27)13-6-7-13/h1-5,8-13H,6-7H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against human p21 deficient cell (p21+/+) proliferation				Bioorg Med Chem Lett 15: 3763-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.127 BindingDB Entry DOI: 10.7270/Q2XG9SB7
					More data for this Ligand-Target Pair
CDK-interacting protein 1 (Homo sapiens (Human))	BDBM50410001 (CHEMBL368233) Show SMILES O=C(Nc1cccc(c1)-c1ccnc2c(cnn12)C(=O)c1cccs1)C1CC1 Show InChI InChI=1S/C21H16N4O2S/c26-19(18-5-2-10-28-18)16-12-23-25-17(8-9-22-20(16)25)14-3-1-4-15(11-14)24-21(27)13-6-7-13/h1-5,8-13H,6-7H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against p21 deficient cell (p21-/-) proliferation				Bioorg Med Chem Lett 15: 3763-6 (2005) Article DOI: 10.1016/j.bmcl.2005.05.127 BindingDB Entry DOI: 10.7270/Q2XG9SB7
					More data for this Ligand-Target Pair