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BDBM50410041 CHEMBL178951

SMILES: NC(C=O)c1cccc(c1)N1[C@H](Cc2ccccc2)[C@H](O)[C@@H](CCc2ccccc2)N(C1=O)c1cccc(c1)C(=N)NO

InChI Key: InChIKey=MXBARTQGOVFAGD-MQKNSBLOSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410041   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Human immunodeficiency virus type 1 protease


(Human immunodeficiency virus type 1)		BDBM50410041
PNG
(CHEMBL178951)
Show SMILES NC(C=O)c1cccc(c1)N1[C@H](Cc2ccccc2)[C@H](O)[C@@H](CCc2ccccc2)N(C1=O)c1cccc(c1)C(=N)NO
Show InChI InChI=1S/C34H35N5O4/c35-29(22-40)25-13-7-15-27(20-25)39-31(19-24-11-5-2-6-12-24)32(41)30(18-17-23-9-3-1-4-10-23)38(34(39)42)28-16-8-14-26(21-28)33(36)37-43/h1-16,20-22,29-32,41,43H,17-19,35H2,(H2,36,37)/t29?,30-,31-,32-/m1/s1
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.0182n/an/an/an/an/an/an/an/a



Clarkson University

Curated by ChEMBL


Assay Description
Antiviral activity potency was assessed by measuring effect on the accumulation of viral RNA transcripts 3 days after infection of MT-2 cells with HI...

Bioorg Med Chem Lett 15: 3767-70 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.087
BindingDB Entry DOI: 10.7270/Q2SQ91KF
More data for this
Ligand-Target Pair