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SMILES: C[C@H](NC(=O)\C=C\c1ccccc1F)c1cccc(c1)-n1cncn1

InChI Key: InChIKey=KPXTWHYAWJDFLL-HBWSCVEGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410078   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily KQT member 2


(Mus musculus)		BDBM50410078
PNG
(CHEMBL182734)
Show SMILES C[C@H](NC(=O)\C=C\c1ccccc1F)c1cccc(c1)-n1cncn1
Show InChI InChI=1S/C19H17FN4O/c1-14(16-6-4-7-17(11-16)24-13-21-12-22-24)23-19(25)10-9-15-5-2-3-8-18(15)20/h2-14H,1H3,(H,23,25)/b10-9+/t14-/m0/s1
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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 330n/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Effect on outward potassium currents in whole-cell patchclamp assay of HEK 293 cells expressing cloned mouse KCNQ2 channel at -40 mV

Bioorg Med Chem Lett 15: 363-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.065
BindingDB Entry DOI: 10.7270/Q2J967KG
More data for this
Ligand-Target Pair