BindingDB logo
myBDB logout

null

SMILES: C[C@H](NC(=O)\C=C\c1ccccc1F)c1cccc(c1)-c1cnccn1

InChI Key: InChIKey=SRDZBCSIQDVOKY-FEAKQIBJSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410083   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily KQT member 2


(Mus musculus)		BDBM50410083
PNG
(CHEMBL183908)
Show SMILES C[C@H](NC(=O)\C=C\c1ccccc1F)c1cccc(c1)-c1cnccn1
Show InChI InChI=1S/C21H18FN3O/c1-15(25-21(26)10-9-16-5-2-3-8-19(16)22)17-6-4-7-18(13-17)20-14-23-11-12-24-20/h2-15H,1H3,(H,25,26)/b10-9+/t15-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 370n/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Effect on outward potassium currents in whole-cell patchclamp assay of HEK 293 cells expressing cloned mouse KCNQ2 channel at -40 mV

Bioorg Med Chem Lett 15: 363-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.065
BindingDB Entry DOI: 10.7270/Q2J967KG
More data for this
Ligand-Target Pair