BDBM50410509 CHEMBL196585::SJ000143975
SMILES: Oc1ccc(cc1)C(c1ccc(O)cc1)C(Cl)(Cl)Cl
InChI Key: InChIKey=IUGDILGOLSSKNE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Androgen receptor (Rattus norvegicus (Rat)) | BDBM50410509 (CHEMBL196585 | SJ000143975) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 9.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Basel Curated by ChEMBL | Assay Description Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881) | J Med Chem 48: 5666-74 (2005) Article DOI: 10.1021/jm050403f BindingDB Entry DOI: 10.7270/Q2TM7CBZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50410509 (CHEMBL196585 | SJ000143975) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University Curated by ChEMBL | Assay Description Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in... | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50410509 (CHEMBL196585 | SJ000143975) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University Curated by ChEMBL | Assay Description Antagonist activity at ERbeta (unknown origin) expressed in human HeLa cells assessed as inhibition of E2-induced transcriptional activity measured a... | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50410509 (CHEMBL196585 | SJ000143975) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a |
Kyushu University Curated by ChEMBL | Assay Description Agonist activity at ERalpha (unknown origin) expressed in human HeLa cells assessed as transcriptional activation measured after 24 hrs by luciferase... | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50410509 (CHEMBL196585 | SJ000143975) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyushu University Curated by ChEMBL | Assay Description Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc... | Bioorg Med Chem 28: (2020) | |||||||||||
More data for this Ligand-Target Pair |