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BDBM50410553 CHEMBL373125

SMILES: Cc1nc(CCC23CC4CC(CC(C4)C2)C3)c([nH]1)C(=O)Nc1cccc(c1)C(O)=O

InChI Key: InChIKey=DKTWTOWWZXZHNH-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410553   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CCKBR


(RAT)		BDBM50410553
PNG
(CHEMBL373125)
Show SMILES Cc1nc(CCC23CC4CC(CC(C4)C2)C3)c([nH]1)C(=O)Nc1cccc(c1)C(O)=O |TLB:13:8:15:12.14.11,13:12:15:8.7.9,9:10:14:8.7.13,THB:9:8:14:10.15.11,11:10:7:12.14.13,11:12:7:10.15.9|
Show InChI InChI=1S/C24H29N3O3/c1-14-25-20(5-6-24-11-15-7-16(12-24)9-17(8-15)13-24)21(26-14)22(28)27-19-4-2-3-18(10-19)23(29)30/h2-4,10,15-17H,5-9,11-13H2,1H3,(H,25,26)(H,27,28)(H,29,30)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/a 1.55E+3n/an/an/an/an/a



James Black Foundation

Curated by ChEMBL


Assay Description
Antagonist activity against CCK2 receptor estimated from single shifts of pentagastrin concentration-effect curves in the isolated rat stomach

J Med Chem 48: 6803-12 (2005)


Article DOI: 10.1021/jm0490686
BindingDB Entry DOI: 10.7270/Q2PV6MM7
More data for this
Ligand-Target Pair