BDBM50410937 CHEMBL380023

SMILES: Cc1ncccc1Cn1nnnc1-c1cccc(Cl)c1Cl

InChI Key: InChIKey=UYHSACNMUUOJFJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50410937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (P2X7) (Rattus norvegicus (Rat))	BDBM50410937 (CHEMBL380023) Show SMILES Cc1ncccc1Cn1nnnc1-c1cccc(Cl)c1Cl Show InChI InChI=1S/C14H11Cl2N5/c1-9-10(4-3-7-17-9)8-21-14(18-19-20-21)11-5-2-6-12(15)13(11)16/h2-7H,8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of calcium flux by FLIPR				J Med Chem 49: 3659-66 (2006) Article DOI: 10.1021/jm051202e BindingDB Entry DOI: 10.7270/Q2VD70P4
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50410937 (CHEMBL380023) Show SMILES Cc1ncccc1Cn1nnnc1-c1cccc(Cl)c1Cl Show InChI InChI=1S/C14H11Cl2N5/c1-9-10(4-3-7-17-9)8-21-14(18-19-20-21)11-5-2-6-12(15)13(11)16/h2-7H,8H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of calcium flux by FLIPR				J Med Chem 49: 3659-66 (2006) Article DOI: 10.1021/jm051202e BindingDB Entry DOI: 10.7270/Q2VD70P4
					More data for this Ligand-Target Pair