BDBM50410944 CHEMBL207370

SMILES: Fc1ccc(c(Cl)c1C(F)(F)F)-n1nnnc1Cc1cccnc1

InChI Key: InChIKey=FSXOMKBIZUXPLS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50410944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50410944 (CHEMBL207370) Show SMILES Fc1ccc(c(Cl)c1C(F)(F)F)-n1nnnc1Cc1cccnc1 Show InChI InChI=1S/C14H8ClF4N5/c15-13-10(4-3-9(16)12(13)14(17,18)19)24-11(21-22-23-24)6-8-2-1-5-20-7-8/h1-5,7H,6H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of calcium flux by FLIPR				J Med Chem 49: 3659-66 (2006) Article DOI: 10.1021/jm051202e BindingDB Entry DOI: 10.7270/Q2VD70P4
					More data for this Ligand-Target Pair