BDBM50411004 CHEMBL535386

SMILES: CN(C)C(=O)N[C@@H](CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1

InChI Key: InChIKey=WISAGRHYXNSVKU-QFIPXVFZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50411004 (CHEMBL535386) Show SMILES CN(C)C(=O)N[C@@H](CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 |r| Show InChI InChI=1S/C26H31Cl2N5O4/c1-33(2)26(35)30-22(5-3-4-13-29)24(34)25-31-23(37-32-25)16-17-6-9-19(10-7-17)36-14-12-18-8-11-20(27)21(28)15-18/h6-11,15,22H,3-5,12-14,16,29H2,1-2H3,(H,30,35)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Inhibition of human B tryptase				Bioorg Med Chem Lett 16: 3434-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.013 BindingDB Entry DOI: 10.7270/Q2G44RHP
					More data for this Ligand-Target Pair