BDBM50411038 CHEMBL214333

SMILES: CCC1(CC(O)(C(=O)Nc2ccc3c(c2)c(C)noc3=O)C(F)(F)F)CCOc2ccccc12

InChI Key: InChIKey=ODORCXXMUXNBOZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50411038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411038 (CHEMBL214333) Show SMILES CCC1(CC(O)(C(=O)Nc2ccc3c(c2)c(C)noc3=O)C(F)(F)F)CCOc2ccccc12 Show InChI InChI=1S/C24H23F3N2O5/c1-3-22(10-11-33-19-7-5-4-6-18(19)22)13-23(32,24(25,26)27)21(31)28-15-8-9-16-17(12-15)14(2)29-34-20(16)30/h4-9,12,32H,3,10-11,13H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of fluorescent-labeled Dexamethasone binding to GR				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411038 (CHEMBL214333) Show SMILES CCC1(CC(O)(C(=O)Nc2ccc3c(c2)c(C)noc3=O)C(F)(F)F)CCOc2ccccc12 Show InChI InChI=1S/C24H23F3N2O5/c1-3-22(10-11-33-19-7-5-4-6-18(19)22)13-23(32,24(25,26)27)21(31)28-15-8-9-16-17(12-15)14(2)29-34-20(16)30/h4-9,12,32H,3,10-11,13H2,1-2H3,(H,28,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cells				J Med Chem 49: 4216-31 (2006) Checked by Author Article DOI: 10.1021/jm060302x BindingDB Entry DOI: 10.7270/Q2BC40SB
					More data for this Ligand-Target Pair