BDBM50411076 CHEMBL210820

SMILES: Cc1c(Cc2c(Cl)cccc2Cl)nc(Sc2ccc(F)cc2F)[nH]c1=O

InChI Key: InChIKey=UKFUSHNRNJTGQX-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50411076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50411076 (CHEMBL210820) Show SMILES Cc1c(Cc2c(Cl)cccc2Cl)nc(Sc2ccc(F)cc2F)[nH]c1=O Show InChI InChI=1S/C18H12Cl2F2N2OS/c1-9-15(8-11-12(19)3-2-4-13(11)20)23-18(24-17(9)25)26-16-6-5-10(21)7-14(16)22/h2-7H,8H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>6.05E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50411076 (CHEMBL210820) Show SMILES Cc1c(Cc2c(Cl)cccc2Cl)nc(Sc2ccc(F)cc2F)[nH]c1=O Show InChI InChI=1S/C18H12Cl2F2N2OS/c1-9-15(8-11-12(19)3-2-4-13(11)20)23-18(24-17(9)25)26-16-6-5-10(21)7-14(16)22/h2-7H,8H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50411076 (CHEMBL210820) Show SMILES Cc1c(Cc2c(Cl)cccc2Cl)nc(Sc2ccc(F)cc2F)[nH]c1=O Show InChI InChI=1S/C18H12Cl2F2N2OS/c1-9-15(8-11-12(19)3-2-4-13(11)20)23-18(24-17(9)25)26-16-6-5-10(21)7-14(16)22/h2-7H,8H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>6.05E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50411076 (CHEMBL210820) Show SMILES Cc1c(Cc2c(Cl)cccc2Cl)nc(Sc2ccc(F)cc2F)[nH]c1=O Show InChI InChI=1S/C18H12Cl2F2N2OS/c1-9-15(8-11-12(19)3-2-4-13(11)20)23-18(24-17(9)25)26-16-6-5-10(21)7-14(16)22/h2-7H,8H2,1H3,(H,23,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.36E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair