null

SMILES: COc1ccc(Sc2nc(Cc3c(Cl)cccc3Cl)c(C)c(=O)[nH]2)cn1

InChI Key: InChIKey=BXGQMSIGOYPUDR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50411078   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50411078 (CHEMBL211326) Show SMILES COc1ccc(Sc2nc(Cc3c(Cl)cccc3Cl)c(C)c(=O)[nH]2)cn1 Show InChI InChI=1S/C18H15Cl2N3O2S/c1-10-15(8-12-13(19)4-3-5-14(12)20)22-18(23-17(10)24)26-11-6-7-16(25-2)21-9-11/h3-7,9H,8H2,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>6.17E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against HIV1 K103N mutant in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50411078 (CHEMBL211326) Show SMILES COc1ccc(Sc2nc(Cc3c(Cl)cccc3Cl)c(C)c(=O)[nH]2)cn1 Show InChI InChI=1S/C18H15Cl2N3O2S/c1-10-15(8-12-13(19)4-3-5-14(12)20)22-18(23-17(10)24)26-11-6-7-16(25-2)21-9-11/h3-7,9H,8H2,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.52E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against HIV1 Y181C mutant in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50411078 (CHEMBL211326) Show SMILES COc1ccc(Sc2nc(Cc3c(Cl)cccc3Cl)c(C)c(=O)[nH]2)cn1 Show InChI InChI=1S/C18H15Cl2N3O2S/c1-10-15(8-12-13(19)4-3-5-14(12)20)22-18(23-17(10)24)26-11-6-7-16(25-2)21-9-11/h3-7,9H,8H2,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>6.13E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against HIV1 Y188L mutant in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50411078 (CHEMBL211326) Show SMILES COc1ccc(Sc2nc(Cc3c(Cl)cccc3Cl)c(C)c(=O)[nH]2)cn1 Show InChI InChI=1S/C18H15Cl2N3O2S/c1-10-15(8-12-13(19)4-3-5-14(12)20)22-18(23-17(10)24)26-11-6-7-16(25-2)21-9-11/h3-7,9H,8H2,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against wild type HIV1 NL4-3 in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50411078 (CHEMBL211326) Show SMILES COc1ccc(Sc2nc(Cc3c(Cl)cccc3Cl)c(C)c(=O)[nH]2)cn1 Show InChI InChI=1S/C18H15Cl2N3O2S/c1-10-15(8-12-13(19)4-3-5-14(12)20)22-18(23-17(10)24)26-11-6-7-16(25-2)21-9-11/h3-7,9H,8H2,1-2H3,(H,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.68E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Antiviral activity against HIV1 IRLL98 in MT4 cells by MTT assay				Bioorg Med Chem Lett 16: 3541-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.080 BindingDB Entry DOI: 10.7270/Q22Z16RM
					More data for this Ligand-Target Pair