BDBM50411419 CHEMBL233002::SB-814597

SMILES: Fc1ccc(C(=O)Nc2sc3CCCCc3c2C#N)c2ccccc12

InChI Key: InChIKey=WTBQHGKQMCKGNX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50411419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50411419 (CHEMBL233002 | SB-814597) Show SMILES Fc1ccc(C(=O)Nc2sc3CCCCc3c2C#N)c2ccccc12 Show InChI InChI=1S/C20H15FN2OS/c21-17-10-9-15(12-5-1-2-6-13(12)17)19(24)23-20-16(11-22)14-7-3-4-8-18(14)25-20/h1-2,5-6,9-10H,3-4,7-8H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human truncated JNK3				Bioorg Med Chem Lett 17: 1296-301 (2007) Article DOI: 10.1016/j.bmcl.2006.12.003 BindingDB Entry DOI: 10.7270/Q2TB1840
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50411419 (CHEMBL233002 | SB-814597) Show SMILES Fc1ccc(C(=O)Nc2sc3CCCCc3c2C#N)c2ccccc12 Show InChI InChI=1S/C20H15FN2OS/c21-17-10-9-15(12-5-1-2-6-13(12)17)19(24)23-20-16(11-22)14-7-3-4-8-18(14)25-20/h1-2,5-6,9-10H,3-4,7-8H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of mitogen-activated protein kinase p38alpha				Bioorg Med Chem Lett 17: 1296-301 (2007) Article DOI: 10.1016/j.bmcl.2006.12.003 BindingDB Entry DOI: 10.7270/Q2TB1840
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50411419 (CHEMBL233002 | SB-814597) Show SMILES Fc1ccc(C(=O)Nc2sc3CCCCc3c2C#N)c2ccccc12 Show InChI InChI=1S/C20H15FN2OS/c21-17-10-9-15(12-5-1-2-6-13(12)17)19(24)23-20-16(11-22)14-7-3-4-8-18(14)25-20/h1-2,5-6,9-10H,3-4,7-8H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant full length JNK1alpha1				Bioorg Med Chem Lett 17: 1296-301 (2007) Article DOI: 10.1016/j.bmcl.2006.12.003 BindingDB Entry DOI: 10.7270/Q2TB1840
					More data for this Ligand-Target Pair