BDBM50411464 CHEMBL392739
SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CNC(=O)NC(=O)c2ccccc2O)[C@@H](O)[C@H]1O
InChI Key: InChIKey=HNQSCVPQTCIJPO-CNEMSGBDSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2,3-dihydroxybenzoate-AMP ligase (Mycobacterium tuberculosis) | BDBM50411464 (CHEMBL392739) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis recombinant MbtA expressed in Escherichia coli by ATP/PPi exchange assay | J Med Chem 50: 6080-94 (2007) Article DOI: 10.1021/jm070905o BindingDB Entry DOI: 10.7270/Q298887N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2,3-dihydroxybenzoate-AMP ligase (Mycobacterium tuberculosis) | BDBM50411464 (CHEMBL392739) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis BAG RV143 MbtA expressed in Escherichia coli BL21 (DE3) assessed as ATP-[32P]PPi exchange by liquid scintill... | J Med Chem 51: 7154-60 (2009) Article DOI: 10.1021/jm800668u BindingDB Entry DOI: 10.7270/Q2ZK5HXC | |||||||||||
More data for this Ligand-Target Pair |