null

SMILES: CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12

InChI Key: InChIKey=YTXMUOSDKIUWKU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50411485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of fluorescent labeled Dexamethasone from glucocorticoid receptor				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells transfected with MMTV luciferase reporter gene assessed as inhibition of dexametha...				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of fluorescent labeled Dexamethasone from glucocorticoid receptor				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	61.7	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by MMTV transactivation assay				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	64.6	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by MMTV transactivation assay				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50411485 (CHEMBL235800) Show SMILES CCC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc12 Show InChI InChI=1S/C24H26F3NO/c1-2-22(13-7-10-17-8-3-5-11-20(17)22)16-23(29,24(25,26)27)15-19-14-18-9-4-6-12-21(18)28-19/h3-6,8-9,11-12,14,28-29H,2,7,10,13,15-16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of fluorescent labeled Dexamethasone from glucocorticoid receptor				J Med Chem 50: 6519-34 (2007) Article DOI: 10.1021/jm070778w BindingDB Entry DOI: 10.7270/Q21R6RRR
					More data for this Ligand-Target Pair