BDBM50411620 CHEMBL272186

SMILES: CCOC(=O)c1cc2ccc3c4cccc(Cl)c4[nH]c3c2[nH]1

InChI Key: InChIKey=RWGIHVNNDIDABH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 1 (CDK1) (Homo sapiens (Human))	BDBM50411620 (CHEMBL272186) Show SMILES CCOC(=O)c1cc2ccc3c4cccc(Cl)c4[nH]c3c2[nH]1 Show InChI InChI=1S/C17H13ClN2O2/c1-2-22-17(21)13-8-9-6-7-11-10-4-3-5-12(18)15(10)20-16(11)14(9)19-13/h3-8,19-20H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
					More data for this Ligand-Target Pair