BDBM50411623 CHEMBL272399

SMILES: CCOC(=O)c1cc2ccc3c4cc(C)ccc4[nH]c3c2[nH]1

InChI Key: InChIKey=KWGMPSIMTBPUCP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 1 (CDK1) (Homo sapiens (Human))	BDBM50411623 (CHEMBL272399) Show SMILES CCOC(=O)c1cc2ccc3c4cc(C)ccc4[nH]c3c2[nH]1 Show InChI InChI=1S/C18H16N2O2/c1-3-22-18(21)15-9-11-5-6-12-13-8-10(2)4-7-14(13)19-17(12)16(11)20-15/h4-9,19-20H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Inhibition of CDK1/cyclin B by MESACUP assay				J Med Chem 51: 1048-52 (2008) Article DOI: 10.1021/jm0700666 BindingDB Entry DOI: 10.7270/Q2RB75TC
					More data for this Ligand-Target Pair