Found 4 hits for monomerid = 50411707 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM50411707
(CHEMBL402016)Show SMILES Cc1ccc2c(cccc2n1)-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(F)(F)F)n1C Show InChI InChI=1S/C28H27F3N6OS/c1-17-7-8-20-21(5-3-6-22(20)32-17)25-34-35-27(36(25)2)39-14-4-11-37-12-9-18-15-23-24(16-19(18)10-13-37)38-26(33-23)28(29,30)31/h3,5-8,15-16H,4,9-14H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 50.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assay |
Bioorg Med Chem Lett 18: 901-7 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.066
BindingDB Entry DOI: 10.7270/Q2MK6F32 |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50411707
(CHEMBL402016)Show SMILES Cc1ccc2c(cccc2n1)-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(F)(F)F)n1C Show InChI InChI=1S/C28H27F3N6OS/c1-17-7-8-20-21(5-3-6-22(20)32-17)25-34-35-27(36(25)2)39-14-4-11-37-12-9-18-15-23-24(16-19(18)10-13-37)38-26(33-23)28(29,30)31/h3,5-8,15-16H,4,9-14H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at dopamine D2 receptor by GTPgammaS binding assay |
Bioorg Med Chem Lett 18: 901-7 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.066
BindingDB Entry DOI: 10.7270/Q2MK6F32 |
More data for this
Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50411707
(CHEMBL402016)Show SMILES Cc1ccc2c(cccc2n1)-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(F)(F)F)n1C Show InChI InChI=1S/C28H27F3N6OS/c1-17-7-8-20-21(5-3-6-22(20)32-17)25-34-35-27(36(25)2)39-14-4-11-37-12-9-18-15-23-24(16-19(18)10-13-37)38-26(33-23)28(29,30)31/h3,5-8,15-16H,4,9-14H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at histamine H1 receptor by FLIPR assay |
Bioorg Med Chem Lett 18: 901-7 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.066
BindingDB Entry DOI: 10.7270/Q2MK6F32 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50411707
(CHEMBL402016)Show SMILES Cc1ccc2c(cccc2n1)-c1nnc(SCCCN2CCc3cc4nc(oc4cc3CC2)C(F)(F)F)n1C Show InChI InChI=1S/C28H27F3N6OS/c1-17-7-8-20-21(5-3-6-22(20)32-17)25-34-35-27(36(25)2)39-14-4-11-37-12-9-18-15-23-24(16-19(18)10-13-37)38-26(33-23)28(29,30)31/h3,5-8,15-16H,4,9-14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]Dofetilide from human ERG |
Bioorg Med Chem Lett 18: 901-7 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.066
BindingDB Entry DOI: 10.7270/Q2MK6F32 |
More data for this
Ligand-Target Pair | |
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