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SMILES: OCc1ccc(OC2CCN(CC3CCN(CC3)c3cccc(c3)C(O)=O)CC2)cc1Cl

InChI Key: InChIKey=GLWRKCYINJIIFZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50411750   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))		BDBM50411750
PNG
(CHEMBL270116)
Show SMILES OCc1ccc(OC2CCN(CC3CCN(CC3)c3cccc(c3)C(O)=O)CC2)cc1Cl
Show InChI InChI=1S/C25H31ClN2O4/c26-24-15-23(5-4-20(24)17-29)32-22-8-10-27(11-9-22)16-18-6-12-28(13-7-18)21-3-1-2-19(14-21)25(30)31/h1-5,14-15,18,22,29H,6-13,16-17H2,(H,30,31)
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Article
PubMed
n/an/a 5.13E+8n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from human recombinant ERG potassium channel expressed in HEK293 cells by patch clamp method

J Med Chem 51: 1162-78 (2008)


Article DOI: 10.1021/jm070543k
BindingDB Entry DOI: 10.7270/Q2C24XMG
More data for this
Ligand-Target Pair