BDBM50412136 CHEMBL495159

SMILES: CCCCCCC(=O)NNc1ccccc1C

InChI Key: InChIKey=YHCZXYOUQUJSAY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (P2X7) (Rattus norvegicus (Rat))	BDBM50412136 (CHEMBL495159) Show SMILES CCCCCCC(=O)NNc1ccccc1C Show InChI InChI=1S/C14H22N2O/c1-3-4-5-6-11-14(17)16-15-13-10-8-7-9-12(13)2/h7-10,15H,3-6,11H2,1-2H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assay				J Med Chem 51: 3030-4 (2008) Article DOI: 10.1021/jm701516f BindingDB Entry DOI: 10.7270/Q2959JR1
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50412136 (CHEMBL495159) Show SMILES CCCCCCC(=O)NNc1ccccc1C Show InChI InChI=1S/C14H22N2O/c1-3-4-5-6-11-14(17)16-15-13-10-8-7-9-12(13)2/h7-10,15H,3-6,11H2,1-2H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assay				J Med Chem 51: 3030-4 (2008) Article DOI: 10.1021/jm701516f BindingDB Entry DOI: 10.7270/Q2959JR1
					More data for this Ligand-Target Pair