BDBM50412208 CHEMBL493254

SMILES: CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc3CNCCc3c2)cc1C

InChI Key: InChIKey=ROVIYOLKVNVZKS-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50412208 (CHEMBL493254) Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc3CNCCc3c2)cc1C Show InChI InChI=1S/C25H29ClN4O2/c1-16(2)15-32-23-7-6-22(26)12-21(23)14-30-17(3)10-24(29-30)28-25(31)19-4-5-20-13-27-9-8-18(20)11-19/h4-7,10-12,16,27H,8-9,13-15H2,1-3H3,(H,28,29,31)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity of human PGE2 receptor expressed in CHOK1 cells assessed as inhibition of intracellular calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 18: 4027-32 (2008) Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50412208 (CHEMBL493254) Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(NC(=O)c2ccc3CNCCc3c2)cc1C Show InChI InChI=1S/C25H29ClN4O2/c1-16(2)15-32-23-7-6-22(26)12-21(23)14-30-17(3)10-24(29-30)28-25(31)19-4-5-20-13-27-9-8-18(20)11-19/h4-7,10-12,16,27H,8-9,13-15H2,1-3H3,(H,28,29,31)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 18: 4027-32 (2008) Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7
					More data for this Ligand-Target Pair