BDBM50412237 CHEMBL492238

SMILES: CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN(C)C)cc1

InChI Key: InChIKey=VXHYDBRIBAUJIE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50412237 (CHEMBL492238) Show SMILES CC(C)COc1ccc(Cl)cc1Cn1nc(cc1C)C(=O)Nc1ccc(CN(C)C)cc1 Show InChI InChI=1S/C25H31ClN4O2/c1-17(2)16-32-24-11-8-21(26)13-20(24)15-30-18(3)12-23(28-30)25(31)27-22-9-6-19(7-10-22)14-29(4)5/h6-13,17H,14-16H2,1-5H3,(H,27,31)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 18: 4027-32 (2008) Article DOI: 10.1016/j.bmcl.2008.05.118 BindingDB Entry DOI: 10.7270/Q2NC62F7
					More data for this Ligand-Target Pair