BDBM50412248 CHEMBL442815

SMILES: CO\N=C\c1ccccc1OC(C)C1=NCCN1

InChI Key: InChIKey=YTQHOBJMFUQZEK-CXUHLZMHSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50412248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50412248 (CHEMBL442815) Show SMILES CO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:14| Show InChI InChI=1S/C13H17N3O2/c1-10(13-14-7-8-15-13)18-12-6-4-3-5-11(12)9-16-17-2/h3-6,9-10H,7-8H2,1-2H3,(H,14,15)/b16-9+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2A receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50412248 (CHEMBL442815) Show SMILES CO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:14| Show InChI InChI=1S/C13H17N3O2/c1-10(13-14-7-8-15-13)18-12-6-4-3-5-11(12)9-16-17-2/h3-6,9-10H,7-8H2,1-2H3,(H,14,15)/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2B receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50412248 (CHEMBL442815) Show SMILES CO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:14| Show InChI InChI=1S/C13H17N3O2/c1-10(13-14-7-8-15-13)18-12-6-4-3-5-11(12)9-16-17-2/h3-6,9-10H,7-8H2,1-2H3,(H,14,15)/b16-9+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic Alpha-2C receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50412248 (CHEMBL442815) Show SMILES CO\N=C\c1ccccc1OC(C)C1=NCCN1 |t:14| Show InChI InChI=1S/C13H17N3O2/c1-10(13-14-7-8-15-13)18-12-6-4-3-5-11(12)9-16-17-2/h3-6,9-10H,7-8H2,1-2H3,(H,14,15)/b16-9+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	501	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic Alpha-2C receptor expressed in CHO cells assessed as stimulation of extracellular acidification				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair