BDBM50412259 CHEMBL492647

SMILES: COC1(COc2c(O1)cccc2-c1ccccc1)C1=NCCN1

InChI Key: InChIKey=NXCHMDJNSMDGIA-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412259   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50412259 (CHEMBL492647) Show SMILES COC1(COc2c(O1)cccc2-c1ccccc1)C1=NCCN1 |t:21| Show InChI InChI=1S/C18H18N2O3/c1-21-18(17-19-10-11-20-17)12-22-16-14(8-5-9-15(16)23-18)13-6-3-2-4-7-13/h2-9H,10-12H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]RS79948-197 from human recombinant adrenergic alpha2A receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50412259 (CHEMBL492647) Show SMILES COC1(COc2c(O1)cccc2-c1ccccc1)C1=NCCN1 |t:21| Show InChI InChI=1S/C18H18N2O3/c1-21-18(17-19-10-11-20-17)12-22-16-14(8-5-9-15(16)23-18)13-6-3-2-4-7-13/h2-9H,10-12H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Camerino Curated by ChEMBL					Assay Description Agonist activity at human recombinant adrenergic alpha2B receptor expressed in CHO cells				J Med Chem 51: 4289-99 (2008) Article DOI: 10.1021/jm800250z BindingDB Entry DOI: 10.7270/Q2HQ4147
					More data for this Ligand-Target Pair