Found 6 hits for monomerid = 50412435 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50412435
(CHEMBL484216)Show SMILES CC(COc1cccc2nc(C)ccc12)N1CCC(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C27H31N3O3/c1-18-6-8-22-23(28-18)4-3-5-25(22)32-16-19(2)30-12-10-20(11-13-30)14-21-7-9-26-24(15-21)29-27(31)17-33-26/h3-9,15,19-20H,10-14,16-17H2,1-2H3,(H,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 39.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50412435
(CHEMBL484216)Show SMILES CC(COc1cccc2nc(C)ccc12)N1CCC(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C27H31N3O3/c1-18-6-8-22-23(28-18)4-3-5-25(22)32-16-19(2)30-12-10-20(11-13-30)14-21-7-9-26-24(15-21)29-27(31)17-33-26/h3-9,15,19-20H,10-14,16-17H2,1-2H3,(H,29,31) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 50.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50412435
(CHEMBL484216)Show SMILES CC(COc1cccc2nc(C)ccc12)N1CCC(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C27H31N3O3/c1-18-6-8-22-23(28-18)4-3-5-25(22)32-16-19(2)30-12-10-20(11-13-30)14-21-7-9-26-24(15-21)29-27(31)17-33-26/h3-9,15,19-20H,10-14,16-17H2,1-2H3,(H,29,31) | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1A receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50412435
(CHEMBL484216)Show SMILES CC(COc1cccc2nc(C)ccc12)N1CCC(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C27H31N3O3/c1-18-6-8-22-23(28-18)4-3-5-25(22)32-16-19(2)30-12-10-20(11-13-30)14-21-7-9-26-24(15-21)29-27(31)17-33-26/h3-9,15,19-20H,10-14,16-17H2,1-2H3,(H,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1B receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50412435
(CHEMBL484216)Show SMILES CC(COc1cccc2nc(C)ccc12)N1CCC(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C27H31N3O3/c1-18-6-8-22-23(28-18)4-3-5-25(22)32-16-19(2)30-12-10-20(11-13-30)14-21-7-9-26-24(15-21)29-27(31)17-33-26/h3-9,15,19-20H,10-14,16-17H2,1-2H3,(H,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50412435
(CHEMBL484216)Show SMILES CC(COc1cccc2nc(C)ccc12)N1CCC(Cc2ccc3OCC(=O)Nc3c2)CC1 Show InChI InChI=1S/C27H31N3O3/c1-18-6-8-22-23(28-18)4-3-5-25(22)32-16-19(2)30-12-10-20(11-13-30)14-21-7-9-26-24(15-21)29-27(31)17-33-26/h3-9,15,19-20H,10-14,16-17H2,1-2H3,(H,29,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]5HT from human cloned 5HT1D receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 5581-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.08.110
BindingDB Entry DOI: 10.7270/Q2KH0PKZ |
More data for this
Ligand-Target Pair | |
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