BDBM50412452 CHEMBL212869

SMILES: CC1CC(C)CN(Cc2ccc(cc2)-c2ccc(CN3CC(C)CC(C)C3)cc2)C1

InChI Key: InChIKey=LJPGMCFDZQFOND-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50412452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412452 (CHEMBL212869) Show SMILES CC1CC(C)CN(Cc2ccc(cc2)-c2ccc(CN3CC(C)CC(C)C3)cc2)C1 Show InChI InChI=1S/C28H40N2/c1-21-13-22(2)16-29(15-21)19-25-5-9-27(10-6-25)28-11-7-26(8-12-28)20-30-17-23(3)14-24(4)18-30/h5-12,21-24H,13-20H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor transfected in SK-N-MC cells				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412452 (CHEMBL212869) Show SMILES CC1CC(C)CN(Cc2ccc(cc2)-c2ccc(CN3CC(C)CC(C)C3)cc2)C1 Show InChI InChI=1S/C28H40N2/c1-21-13-22(2)16-29(15-21)19-25-5-9-27(10-6-25)28-11-7-26(8-12-28)20-30-17-23(3)14-24(4)18-30/h5-12,21-24H,13-20H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412452 (CHEMBL212869) Show SMILES CC1CC(C)CN(Cc2ccc(cc2)-c2ccc(CN3CC(C)CC(C)C3)cc2)C1 Show InChI InChI=1S/C28H40N2/c1-21-13-22(2)16-29(15-21)19-25-5-9-27(10-6-25)28-11-7-26(8-12-28)20-30-17-23(3)14-24(4)18-30/h5-12,21-24H,13-20H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in rat brain membranes				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412452 (CHEMBL212869) Show SMILES CC1CC(C)CN(Cc2ccc(cc2)-c2ccc(CN3CC(C)CC(C)C3)cc2)C1 Show InChI InChI=1S/C28H40N2/c1-21-13-22(2)16-29(15-21)19-25-5-9-27(10-6-25)28-11-7-26(8-12-28)20-30-17-23(3)14-24(4)18-30/h5-12,21-24H,13-20H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membrane				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50412452 (CHEMBL212869) Show SMILES CC1CC(C)CN(Cc2ccc(cc2)-c2ccc(CN3CC(C)CC(C)C3)cc2)C1 Show InChI InChI=1S/C28H40N2/c1-21-13-22(2)16-29(15-21)19-25-5-9-27(10-6-25)28-11-7-26(8-12-28)20-30-17-23(3)14-24(4)18-30/h5-12,21-24H,13-20H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.38E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H4 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair