BDBM50412474 CHEMBL211370

SMILES: O=C1CCCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1

InChI Key: InChIKey=DQOHQFYLWISJMK-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50412474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412474 (CHEMBL211370) Show SMILES O=C1CCCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C24H30N2O/c27-24-6-2-5-17-26(24)19-21-9-13-23(14-10-21)22-11-7-20(8-12-22)18-25-15-3-1-4-16-25/h7-14H,1-6,15-19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	46.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor expressed in SK-N-MC cells				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50412474 (CHEMBL211370) Show SMILES O=C1CCCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C24H30N2O/c27-24-6-2-5-17-26(24)19-21-9-13-23(14-10-21)22-11-7-20(8-12-22)18-25-15-3-1-4-16-25/h7-14H,1-6,15-19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from human histamine H3 receptor transfected in SK-N-MC cells				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412474 (CHEMBL211370) Show SMILES O=C1CCCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C24H30N2O/c27-24-6-2-5-17-26(24)19-21-9-13-23(14-10-21)22-11-7-20(8-12-22)18-25-15-3-1-4-16-25/h7-14H,1-6,15-19H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in Wistar rat brain membrane				Bioorg Med Chem 16: 9911-24 (2008) Article DOI: 10.1016/j.bmc.2008.10.029 BindingDB Entry DOI: 10.7270/Q2FQ9XVP
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50412474 (CHEMBL211370) Show SMILES O=C1CCCCN1Cc1ccc(cc1)-c1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C24H30N2O/c27-24-6-2-5-17-26(24)19-21-9-13-23(14-10-21)22-11-7-20(8-12-22)18-25-15-3-1-4-16-25/h7-14H,1-6,15-19H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]RAMHA from histamine H3 receptor in rat brain membranes				Bioorg Med Chem Lett 16: 4063-7 (2006) Article DOI: 10.1016/j.bmcl.2006.04.092 BindingDB Entry DOI: 10.7270/Q2FX7D7Q
					More data for this Ligand-Target Pair