BDBM50412484 CHEMBL461730

SMILES: CNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1C

InChI Key: InChIKey=KSOGXYLRPYIFSI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50412484 (CHEMBL461730) Show SMILES CNc1nc(nc2ccc(Cl)cc12)N1CCN(C)CC1C Show InChI InChI=1S/C15H20ClN5/c1-10-9-20(3)6-7-21(10)15-18-13-5-4-11(16)8-12(13)14(17-2)19-15/h4-5,8,10H,6-7,9H2,1-3H3,(H,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cells				J Med Chem 51: 7855-65 (2008) Article DOI: 10.1021/jm800876b BindingDB Entry DOI: 10.7270/Q29Z964R
					More data for this Ligand-Target Pair