BDBM50412650 CHEMBL297914

SMILES: Oc1ccc(NC(=O)c2cc(Cl)ccc2O)c(c1)[N+]([O-])=O

InChI Key: InChIKey=OHDHEIYNYTUBMD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel alpha/beta 1 (Homo sapiens (Human))	BDBM50412650 (CHEMBL297914) Show SMILES Oc1ccc(NC(=O)c2cc(Cl)ccc2O)c(c1)[N+]([O-])=O Show InChI InChI=1S/C13H9ClN2O5/c14-7-1-4-12(18)9(5-7)13(19)15-10-3-2-8(17)6-11(10)16(20)21/h1-6,17-18H,(H,15,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile tone				Bioorg Med Chem 17: 319-25 (2008) Article DOI: 10.1016/j.bmc.2008.10.068 BindingDB Entry DOI: 10.7270/Q2P84D59
					More data for this Ligand-Target Pair