BDBM50412677 CHEMBL465376

SMILES: Oc1ccc(Cl)cc1C(=O)Nc1cccnc1

InChI Key: InChIKey=PHRCJJDVUZDVCX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-activated potassium channel subunit alpha-1 (Homo sapiens (Human))	BDBM50412677 (CHEMBL465376) Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1cccnc1 Show InChI InChI=1S/C12H9ClN2O2/c13-8-3-4-11(16)10(6-8)12(17)15-9-2-1-5-14-7-9/h1-7,16H,(H,15,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Activation of BK channel-mediated vasorelaxation activity assessed as reduction in KCl-induced contractile tone				Bioorg Med Chem 17: 319-25 (2008) Article DOI: 10.1016/j.bmc.2008.10.068 BindingDB Entry DOI: 10.7270/Q2P84D59
					More data for this Ligand-Target Pair