BDBM50412716 AC-98170::CHEMBL494303

SMILES: CC(=NNC(=O)[C@H]1[C@@H](CNC1=O)c1ccccc1)c1cccs1

InChI Key: InChIKey=GNFXCDMTRHENBV-ZFWWWQNUSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM50412716 (AC-98170 | CHEMBL494303) Show SMILES CC(=NNC(=O)[C@H]1[C@@H](CNC1=O)c1ccccc1)c1cccs1 |r,w:2.2| Show InChI InChI=1S/C17H17N3O2S/c1-11(14-8-5-9-23-14)19-20-17(22)15-13(10-18-16(15)21)12-6-3-2-4-7-12/h2-9,13,15H,10H2,1H3,(H,18,21)(H,20,22)/t13-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals AB Curated by ChEMBL					Assay Description Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assay				J Med Chem 51: 5490-3 (2008) Article DOI: 10.1021/jm800754r BindingDB Entry DOI: 10.7270/Q290251P
					More data for this Ligand-Target Pair