BDBM50412800 CHEMBL515532

SMILES: COc1ccc(N2CCc3c2nc(C)cc3-n2ccc(n2)N2CCN(C)C2=O)c(C)c1

InChI Key: InChIKey=WINAPCAJDORCHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412800   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50412800 (CHEMBL515532) Show SMILES COc1ccc(N2CCc3c2nc(C)cc3-n2ccc(n2)N2CCN(C)C2=O)c(C)c1 Show InChI InChI=1S/C23H26N6O2/c1-15-13-17(31-4)5-6-19(15)27-9-7-18-20(14-16(2)24-22(18)27)29-10-8-21(25-29)28-12-11-26(3)23(28)30/h5-6,8,10,13-14H,7,9,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells				J Med Chem 51: 7370-9 (2009) Article DOI: 10.1021/jm800744m BindingDB Entry DOI: 10.7270/Q2N87C1X
					More data for this Ligand-Target Pair