BDBM50412804 CHEMBL456449

SMILES: COc1ccc(N2CCc3c2nc(C)cc3-n2ccc(n2)N2CCNS2(=O)=O)c(C)c1

InChI Key: InChIKey=JTUKIQHISYGDML-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50412804 (CHEMBL456449) Show SMILES COc1ccc(N2CCc3c2nc(C)cc3-n2ccc(n2)N2CCNS2(=O)=O)c(C)c1 Show InChI InChI=1S/C21H24N6O3S/c1-14-12-16(30-3)4-5-18(14)25-9-6-17-19(13-15(2)23-21(17)25)26-10-7-20(24-26)27-11-8-22-31(27,28)29/h4-5,7,10,12-13,22H,6,8-9,11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	309	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Displacement of [125I]sauvagine from human recombinant CRF1 receptor expressed in CHO cells				J Med Chem 51: 7370-9 (2009) Article DOI: 10.1021/jm800744m BindingDB Entry DOI: 10.7270/Q2N87C1X
					More data for this Ligand-Target Pair