BindingDB logo
myBDB logout

BDBM50412899 CHEMBL515434

SMILES: COc1cccc(CCN(Cc2ccccc2-c2ccc(CN3CCNCC3)cc2)C(=O)Cc2ccccc2)c1

InChI Key: InChIKey=LGCLDAOGSOUDEH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50412899   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Motilin receptor


(Homo sapiens (Human))		BDBM50412899
PNG
(CHEMBL515434)
Show SMILES COc1cccc(CCN(Cc2ccccc2-c2ccc(CN3CCNCC3)cc2)C(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C35H39N3O2/c1-40-33-12-7-10-29(24-33)18-21-38(35(39)25-28-8-3-2-4-9-28)27-32-11-5-6-13-34(32)31-16-14-30(15-17-31)26-37-22-19-36-20-23-37/h2-17,24,36H,18-23,25-27H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.00E+3n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by calcium mobilization-based FLIPR assay

Bioorg Med Chem Lett 18: 6423-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.071
BindingDB Entry DOI: 10.7270/Q2474C3P
More data for this
Ligand-Target Pair