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SMILES: CC(CC(=O)NC(N)=NCCCc1cnc[nH]1)c1nccs1

InChI Key: InChIKey=VNRCMCFRWRKGPN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50413182   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50413182
PNG
(CHEMBL472039)
Show SMILES CC(CC(=O)NC(N)=NCCCc1cnc[nH]1)c1nccs1 |w:8.8|
Show InChI InChI=1S/C14H20N6OS/c1-10(13-17-5-6-22-13)7-12(21)20-14(15)18-4-2-3-11-8-16-9-19-11/h5-6,8-10H,2-4,7H2,1H3,(H,16,19)(H3,15,18,20,21)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 38.9n/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity

J Med Chem 51: 7193-204 (2009)


Article DOI: 10.1021/jm800841w
BindingDB Entry DOI: 10.7270/Q2RN38T6
More data for this
Ligand-Target Pair