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BDBM50414349 CHEMBL564535

SMILES: CN(C)CC(O)Cc1ccc(Cl)c(c1)C(=O)NCC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=XNANHPIYZJMJSP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50414349   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2X purinoceptor 7


(Homo sapiens (Human))		BDBM50414349
PNG
(CHEMBL564535)
Show SMILES CN(C)CC(O)Cc1ccc(Cl)c(c1)C(=O)NCC12CC3CC(CC(C3)C1)C2 |TLB:19:18:21.20.25:23,25:20:27:24.23.26,25:24:27:21.20.19,17:18:21.20.25:23,THB:19:20:23:27.18.26,26:18:21:25.24.23,26:24:21:27.19.18,17:18:21:25.24.23|
Show InChI InChI=1S/C23H33ClN2O2/c1-26(2)13-19(27)8-15-3-4-21(24)20(9-15)22(28)25-14-23-10-16-5-17(11-23)7-18(6-16)12-23/h3-4,9,16-19,27H,5-8,10-14H2,1-2H3,(H,25,28)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.98n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptake

J Med Chem 52: 3123-41 (2009)


Article DOI: 10.1021/jm801528x
BindingDB Entry DOI: 10.7270/Q2251KDR
More data for this
Ligand-Target Pair