BDBM50414497 CHEMBL564064

SMILES: OC(=O)c1cc([nH]n1)N(Cc1cccc(F)c1)Cc1cccc(F)c1

InChI Key: InChIKey=RSYKDSYEZBWUIA-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50414497 (CHEMBL564064) Show SMILES OC(=O)c1cc([nH]n1)N(Cc1cccc(F)c1)Cc1cccc(F)c1 Show InChI InChI=1S/C18H15F2N3O2/c19-14-5-1-3-12(7-14)10-23(11-13-4-2-6-15(20)8-13)17-9-16(18(24)25)21-22-17/h1-9H,10-11H2,(H,21,22)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.33E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109a receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
HM74 nicotinic acid GPCR (Homo sapiens (Human))	BDBM50414497 (CHEMBL564064) Show SMILES OC(=O)c1cc([nH]n1)N(Cc1cccc(F)c1)Cc1cccc(F)c1 Show InChI InChI=1S/C18H15F2N3O2/c19-14-5-1-3-12(7-14)10-23(11-13-4-2-6-15(20)8-13)17-9-16(18(24)25)21-22-17/h1-9H,10-11H2,(H,21,22)(H,24,25)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair